THE MUSHROOM THAT FEEDS THE BRAIN
Neurogenesis, cognition and memory: the benefits of Hericium erinaceus
Long ignored in Europe, Hericium erinaceus, nicknamed “Lion 's Mane ” for its silky texture, is attracting growing interest in neuroscience. And for good reason: this adaptogenic mushroom has a unique effect on the central nervous system, the intestinal microbiota, and emotional balance. A valuable natural combination for preserving mental clarity, strengthening neuronal plasticity, and promoting overall well-being.
A natural NGF booster
What distinguishes Hericium from most medicinal plants and mushrooms is its ability to stimulate the production of NGF (Nerve Growth Factor) , a growth factor involved in the survival, regeneration and differentiation of neurons. Erinacines and hericinones, bioactive compounds extracted from this mushroom, act directly on neurogenesis.
Several studies have shown that Hericium can stimulate the growth of new neurites in the brain, a process crucial for memory, learning, and cognitive recovery after stress or neuronal injury. In humans, preliminary clinical trials have shown positive effects on cognitive function in older adults with mild memory impairment (Mori et al., 2009).
Support against cognitive decline
Brain plasticity, the brain's ability to reorganize itself, tends to diminish with age, chronic stress, or poor lifestyle. Hericium acts as a resilience factor here . By promoting neuronal regeneration, it could help slow cognitive aging, improve concentration, and reduce mild attention disorders.
An ally of the microbiota and digestion
But Hericium isn't just about brain power. It's also known for its digestive benefits: rich in polysaccharides and beta-glucans , it supports the regeneration of intestinal mucosa and helps reduce gastrointestinal inflammation. It also promotes microbiota balance, stimulating the growth of certain beneficial bacteria, making it an excellent support for the gut-brain axis.


Immunity, oxidative stress and inflammation
Lion's Mane mushroom is also a source of immunomodulatory beta-glucans , known to stimulate innate immunity. In addition, its richness in erinacines gives it a notable antioxidant power , capable of limiting damage induced by oxidative stress. Some in vitro research and on animal models have even revealed promising anticancer potential , particularly on gastric, hepatic or colorectal cells - data to be taken with caution but which supports its role in cellular protection.
Mood, anxiety and mental clarity
Finally, Hericium is said to have a positive effect on emotional balance. Some studies have shown modulation of neurotransmitters such as dopamine and serotonin , associated with better resistance to stress and a more stable mood. In anxious or stressed subjects, supplementation has been linked to a reduction in mild depressive symptoms and an increased feeling of mental clarity.
Conclusion
A complete adaptogen, natural neuroprotectant, digestive and emotional regulator, Hericium erinaceus embodies a new generation of nutraceuticals at the crossroads of neuroscience, intestinal health, and functional medicine. A valuable ally for those seeking to support their brain, soothe their mind, and strengthen their inner resilience.